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Investigation of hydrophobic amino acids against moisture on in vitro aerosolization performance of highly hygroscopic spray-dried powders

  • In: Short Communications C1 on Monday, 22 May 2017, 13:30-15:00
  • At: Stockholm (Sweden) (2017)
  • Type: Presentation
  • By: YU, Jiaqi (The University of Sydney, Faculty of Pharmacy, Sydney, Australia)
  • Co-author(s): Jiaqi Yu: Faculty of Pharmacy, The University of Sydney, Sydney, Australia
    Thomas Gengenbach: CSIRO Manufacturing, Melbourne, Australia
    John Denman: Future Industries Institute, University of South Australia, Adelaide, Australia
    Hak-Kim Chan: Faculty of Pharmacy, The University of Sydney, Sydney, Australia
  • Abstract:

    Backgrounds

    Amorphous drugs or excipients may absorb atmospheric moisture, causing powder aggregation and recrystallization. The resulting agglomerates or crystals with changed size and shape would adversely affect the powder dispersion and lung deposition. 

    Aims

    To study the effect of hydrophobic amino acids on moisture protection to

    ..

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Last update 28 September 2023

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