Menu
  • Join
  • Login
  • Contact
 

Search abstracts / presentations


Effect of Drug Uptake Transporters on Fluvastatin Pharmacokinetics in Rats

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-A-067-Tuesday
  • By: OKOCHI, Hideaki (UCSF, BTS, SAN FRANCISCO, United States)
  • Co-author(s): Hideaki Okochi: Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, United States
    Leslie Benet: Department of Bioengineering & Therapeutic Sciences, University of California San Francisco, San Francisco, United States
  • Abstract:

    Backgrounds

    Fluvastatin (FLST), a highly hydrophilic and extensively metabolized HMG-CoA reductase inhibitor, is categorized as Biopharmaceutical Drug Disposition Classification class 1 and suggested not to be affected by drug transporters in in vivo pharmacokinetics (PK). However, the Extended Clearance Classification System suggests that FLST, an

    ..

  • The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 28 September 2023

FIP Congresses