SIG on PK/PD and Systems Pharmacology

Chair: Dr Don Mager (USA)

Vice-Chairs: Prof. Hiroshi Suzuki (Japan) & Dr Masoud Jamei (United Kingdom)

The intensity and time-course of pharmacological effets (pharmacodynamics, PD) are the results of the complex interplay between drug- and system specific properties.

The time-course of drug concentrations (pharmacokinetics, PD) represents the driving force for the response to drugs, and major processes regulating drug exposure include absorption, distribution, metabolism and excretion (ADME / Systems pharmacology).

Clinical outcomes ultimately reflect PK/PD relationships that can be influenced by numerous pharmacological and (patho-)physiological factors.

The PK/PD and Systems Pharmacology SIG provides an international forum for the development and evaluation of methodologies that seek to translate PK/PD principlesfor the optimization of pharmaceutical care. Our goal is to bring together scientists engaged in Systems pharmacology and PK/PD research with clinical pharmacists to foster collaborations and facilitate the generation and dissemination of new approaches for advancing pharmacotherapy.

We also recognize education and training as a core component of this SIG and are working toward educational opportunities for our glbal members and recruitment strategies through state-of-the-art programming at the Annual FIP congress, as well as new electronic and online platforms.

For more information on this SIG, please contact Dr Mager at PK/PDADME@fip.org.