Blood-brain barrier transport and intra-brain distribution of the cyclotide kalata B1

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-099-Tuesday
• By: MELANDER, Erik (Uppsala, Sweden)
• Co-author(s): Erik Melander: Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
  Camilla Eriksson: Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden
  Ulf Göransson: Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden
  Margareta Hammarlund-Udenaes: Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
  
• Abstract:

  Backgrounds

  Cyclotides are a group of stable cyclic peptides containing three disulphide bonds. They are interesting from a drug development perspective, as they can be used as a scaffold for stabilizing linear peptides. One area that would benefit from improved characteristics of therapeutic peptides is the CNS. Therapeutic peptide generally have..

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