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A semi-mechanistic PK/PD model to elucidate levofloxacin-induced killing and resistance development of Escherichia coli
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-072-Monday
- By: GOEBGEN, Eva (Institute of Pharmacy, Department of Clinical Pharmacy and Biochemistry, Berlin, Germany)
- Co-author(s): Eva B. Goebgen: Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany
Sebastian G. Wicha: Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany
Charlotte Kloft: Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany - Abstract:
Backgrounds
Emerging resistance is known to be enhanced by misuse of antibiotics.Aims
This project aimed at elucidating the bacterial killing of levofloxacin (LEV) against and the resistance development of Escherichia coli (E. coli) by semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling.Methods
To describe in vitro data of resistant E.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023