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Prediction of food effect on intestinal drug absorption: Development and evaluation of a new in silico physiological fed state model in GI-Sim
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-C-036-Monday
- By: KARLSSON, Eva (AstraZeneca, Operations, Mölndal, Sweden)
- Co-author(s): Anneli Angerfors: Pharmaceutical technology and development, AstraZeneca, Mölndal, Sweden
Christer Tannergren: Pharmaceutical technology and development, AstraZeneca, Mölndal, Sweden
Erik Sjögren: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Eva Karlsson: Pharmaceutical technology and development, AstraZeneca, Mölndal, Sweden - Abstract:
Backgrounds
Physiologically based in silico models are widely used in the pharmaceutical industry for prediction of in vitro and in vivo drug performance. The models are continuously improved with increased knowledge of the gastrointestinal (GI) physiology and drug absorption process.Aims
The aim of the present study was to develop and evaluate an i.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023