PREPARATION AND EVALUATION OF METHYLATED N-(4-N,N DIMETHYL AMINOBENZYL) CARBOXYMETHYL CHITOSAN AS A NON VIRAL VECTOR FOR GENE DELIVERY

• In: Poster Session
• At: Düsseldorf (Germany) (2015)
• Type: Poster
• By: RAHMANI, Soheila (Faculty of Pharmacy, Tehran University of Medical Sciences, Pharmaceutics, tehran, Iran)
• Co-author(s): Soheila Rahmani
  
• Abstract:

  Chitosan is a biodegradable,biocompatible cationic polymer which has been widely used for gene delivery purposes.However its application has been limited due to its poor solubility in water and low transfection efficiency.

   

  After synthesizing the derivative in 3steps,we use H-NMR and FT-IR for characterization of the polymer.The nanoparticles were

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