Syudy on the pharmacokinetics and bioequivalence of oxybutynin in 8 dogs after a single and multiple oral administration of osmotic pump tablets

• In: SIG Bioavailability/Bioequivalence - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: BB-P-012
• By: DING, Xueying (Second Military Medical University, Shanghai, China)
• Co-author(s): GAO, Shen (Second Military Medical University, SHANGHAI, China)
  LIU, Gang-yi (Xuhui Central Hospotial, SHANGHAI, China)
  YU, Chen (Xuhui Central Hospotial, SHANGHAI, China)
  
• Abstract:

  AIM To study the pharmacokinetics and bioequivalence of self-prepared osmotic pump tablets(OPT) 、imported OPT and immediate-release（IR） tablets of oxybutynin in dogs.METHODS LC-MS method was developed to detect the plasma drug concentration in 9 dogs. Two one-sided T-test and analysis of variance were performed to evaluate the..

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