Unexpected effect of Chinese herbal medicine curcumin on the pharmacokinetics of talinolol in healthy Chinese subjects

• In: Hospital Pharmacy Section - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: HPS-P-010
• By: HE, Juan (Central South University, Changsha, China)
• Co-author(s): Bernd, Terhaag (Arzneimittelwerk Dresden GmbH, RADEBEUL, Germany)
  Zang, Cong (Central South University, CHANGSHA, China)
  Peng, Wenxing (Central South University, CHANGSHA, China)
  
• Abstract:

  Objective To investigate the effect of Chinese herbal medicine curcumin on the pharmacokinetics of the β1 blocker talinolol. Methods In a two-period self-controlled paralleled study, the oral pharmacokinetics of talinolol after consecutive 6-day oral doses of curcumin was investigated in 12 Chinese healthy men. Concentrations of talinolol were

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