Therapeutic drug monitoring of protease inhibitors in hiv pediatric patients.

• In: Hospital Pharmacy Section - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: HPS-P-048
• By: CACERES GUIDO, Paulo Arturo (Hospital de Pediatria Garrahan, Buenos Aires, Argentina)
• Co-author(s): Currás, Verónica (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
  Hocht, Christian (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
  Bologna, Rosa (Hospital de Pediatria Garrahan, BUENOS AIRES, Argentina)
  Mecikovsky, Débora (Hospital de Pediatria Garrahan, BUENOS AIRES, Argentina)
  Rubio, Modesto (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
  Bramuglia, Guillermo (Facultad de Farmacia y Bioquímica (UBA), BUENOS AIRES, Argentina)
  
• Abstract:

  Aims: Since antiretroviral (ARV) drugs show high interindividual pharmacokinetic variability, therapeutic drug monitoring (TDM) can be used to optimize dosage regimens, based on achieving plasma levels within a therapeutic range. Several studies have shown a relationship between plasma levels of HIV protease inhibitors (PI) and treatment outcome,..

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