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Design, synthesis and biological evaluation of imidazole derivatives as novel atypical selective cyclooxygenase-2 inhibitors.
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-019-Monday
- By: KIANI, Azin (Shahid Beheshti University of Medical Sciences, pharmaceutical chemistry, Sari, Iran, Islamic Republic Of)
- Co-author(s): Azin Kiani: Pharmaceutical Chemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic Of
Elham Rezaee: Pharmaceutical Chemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic Of
Sayyed Abbas Tabatabai: Pharmaceutical Chemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic Of - Abstract:
Backgrounds
Nonsteroidal anti-inflammatory drugs block cyclooxygenase isoenzymes (COX-1 and COX-2) and their long term use leads to a number of adverse effects related to normal physiological expression of COX-1, therefore the development of selective COX-2 inhibitors was prompted.Aims
Here a new structure-activity relationship for selective COX-2.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023