The interaction of Staphylococcus aureus coagulase with prothrombin in various organisms

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-059-Tuesday
• By: ALANKO, Ida (Åbo Akademi University, Pharmacy, vaasa, Finland)
• Co-author(s): Ida Alanko: Faculty of Sciences and Engineering, Pharmacy, Åbo Akademi University, Turku, Finland;Department of Clinical Sciences Lund, Division of Infection Medicine, Lund University Biomedical Center, Lund, Sweden
  Clément Naudin: Karolinska Institutet, Solna, Sweden;Department of Clinical Sciences Lund, Division of Infection Medicine, Lund University Biomedical Center, Lund, Sweden
  Rolf Lood: Department of Clinical Sciences Lund, Division of Infection Medicine, Lund University Biomedical Center, Lund, Sweden
  Heiko Herwald: Department of Clinical Sciences Lund, Division of Infection Medicine, Lund University Biomedical Center, Lund, Sweden
  Outi Salo-Ahen: Faculty of Sciences and Engineering, Pharmacy, Åbo Akademi University, Turku, Finland
  Emanuel Smeds: Department of Clinical Sciences Lund, Division of Infection Medicine, Lund University Biomedical Center, Lund, Sweden
  
• Abstract:

  Backgrounds

   
  

  Staphylococcus aureus is an important human pathogen that causes a variety of infectious diseases. S. aureus secretes an enzyme coagulase that activates prothrombin and initiates blood clotting. It has been found that coagulase cannot activate the prothrombin of Mongolian gerbil, Meriones unguiculatus. 

  Aims

  The aim of the study was to
  
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