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Cell surface modification with protein-PEG-lipid connected through a non-natural amino acid on protein

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-B-017-Tuesday
  • By: HIGUCHI, Yuriko (Kyoto University, Pharmaceutical Sciences, Kyoto, Japan)
  • Co-author(s): Yuriko Higuchi: Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
    Kaori Sugita: Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
    Fumiyoshi Yamashita: Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
    Mitsuru Hashida: Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
  • Abstract:

    Backgrounds

    Cell surface modification with protein ligand via PEG-lipid is a promising way to regulate cell-cell interaction in cell therapy. In the preparation of the protein-PEG-lipid conjugates, the conjugation site on the protein ligand should be carefully selected to maintain its structure and function

    Aims

    Cells are modified with mKO2-PEG-DSPE

    ..

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Last update 28 September 2023

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