Integration of mechanistic information generated through systems pharmacology into pharmacoepidemiologic studies aimed at making inferences about the real-life impact of emerging safety concerns

• In: Symposium A4: Systems pharmacology –innovative approaches to drug safety on Wednesday, 24 May 2017, 11:05-11:30
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: WINTERSTEIN, Almut (University of Florida, Gainesville, United States)
• Co-author(s): Almut G Winterstein: Pharmaceutical Outcomes & Policy, University of Florida, Gainesville, United States
  
• Abstract:

  The availability of large billing and electronic health records allows investigation of drug effects in real-world populations that exceed the number and diversity of patients enrolled in clinical trials. Lack of randomization and measurement issues related to use of data that was not collected for research purposes can create severe bias, which

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