Evidence of p-glycoprotein mediated and saturable intestinal absorption of rifampicin in rat

• In: SIG Bioavailability/Bioequivalence Posters
• At: New Orleans (USA) (2004)
• Type: Poster
• Poster code: BB-P009
• By: THANGA MARIAPPAN (NIPER, Pharmaceutical analysis, Mohali, India)
• Co-author(s): Singh, Saranjit (NIPER, MOHALI, India)
  
• Abstract:

  The problem of poor and variable bioavailability of rifampicin is a matter of serious concern because of its narrow therapeutic window. This study was carried out to explore whether efflux mediated and saturable mechanisms play any role towards poor and variable intestinal absorption of rifampicin. In situ segmental permeability of rifampicin at..

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