Comparative bioavailability of two brands of oral sustained-release nitroglycerin tablets

• In: SIG: Bioavailability/Bioequivalence - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: BB-P-012
• By: GHANDFOROUSH-SATTARI, Mohammadreza (Tabriz University of Medical Sciences, Tabriz, Iran)
• Co-author(s): Valizadeh, Hadi (Tabriz University of Medical Sciences, TABRIZ, Iran)
  Zakeri, Parvin (Tabriz University of Medical Sciences, TABRIZ, Iran)
  Mashayekhi, Siminozar (Hematology and Oncology Research Centre, Tabriz, Iran, Iran)
  
• Abstract:

  Nitroglycerin (GTN, glyceryl trinitrate) has been used in the treatment of angina pectoris for more than a century. Following oral administration, GTN undergoes extensive first pass hepatic metabolism, thus for the pharmacokinetic study of oral GTN, its main two stable metabolites; 1,2-dinitroglycerin (1,2-GDN) and 1,3-dinitroglycerin (1,3-GDN)..

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