Homocysteine induces cell proliferation through up-regulation of cyclin d1 expression via ?1 integrin/akt/p70s6k signaling pathway in human vascular smooth muscle cells

• In: Clinical Biology - Posters
• At: Istanbul (Turkey) (2009)
• Type: Poster
• Poster code: CBS-P-004
• By: CHEN, Heng-Jung (Dept. of Nursing, Chung Jen College of Nursing, Health Sciences and Management, Chiayi, China Taiwan)
• Co-author(s): Chen, Cheng-Nan (Department of Biochemical Science and Technology, National Chiayi University, CHIAYI, China Taiwan)
  
• Abstract:

  The molecular basis of homocysteine-induced cell proliferation in human vascular smooth muscle cells (SMCs) remains unclear. We investigated the mechanism by which homocysteine affects the cyclin D1 expression in human umbilical artery smooth muscle cells (HUASMCs). Homocysteine treatment for 24 and 48 h induced proliferation of cells...

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