A genetic variant in CYP3A4 gene is associated with increased risk of coronary heart disease in Han Chinese

• In: Clinical Biology Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: CBS-P-010
• By: HE, Baoxia (Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, China)
• Co-author(s): Shi, Lei (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  Qiu, Jian (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  Tao, Liang (Sun Yat-sen University, GUANGZHOU, China)
  Li, Rui (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  Yang, Liang (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  Zhao, Shujin (Guangzhou General Hospital of Guangzhou Military Command, GUANGZHOU, China)
  
• Abstract:

  Background: There are accumulating evidences that cytochrome P450 (CYP) enzymes play crucial roles in cardiovascular disease. CYP3A4 is a major member of the CYP enzymes. Most recently, a novel mutation in the CYP3A4 gene, named CYP3A4*1G (rs2242480), has been identified, and in found to be associated with the activity of CYP3A4 enzyme. The aim of

  ..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login