Simvastatin reverses cyclosporin a-induced vascular dysfunction in male rats: a biochemical, pharmacological and histopathological study

• In: Clinical Biology Section - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: CBS-P-007
• By: HELMY, Mai (Faculty of Pharmacy, Alexandria, PHARMACOLOGY, Alexandria, Egypt)
• Co-author(s): Abdel-Galil (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
  El Sawy (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
  Saad (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
  Omar (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
  
• Abstract:

  Cyclosporin A (CyA) is the immunosuppressant most frequently used in transplant surgery and in the management of autoimmune diseases. CyA-induced oxidative stress together with dyslipidemia have been implicated in the pathogenesis of vascular dysfunction associating CyA therapy. The present study investigated the possible protective effect of..

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