Comparison of UPLC-MS-MS and Architect i1000 immunology analyzer methods for Cyclosporine A and Tacrolimus therapeutic drug monitoring

• In: Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: HPS-P-136
• By: LIU, Xiao (China-Japan Friendship Hospital, Pharmacy Department, Beijing, China)
• Co-author(s): Chen, W. (China-Japan Friendship Hospital, Beijing, China)
  Cui, G. (China-Japan Friendship Hospital, Beijing, China)
  Li, P. (China-Japan Friendship Hospital, Beijing, China)
  Zhang, X. (China-Japan Friendship Hospital, Beijing, China)
  
• Abstract:

  BACKGROUD Cyclosporine A (CsA) and Tacrolimus (FK506) are immunosuppressive drugs used extensively in human transplants of solid organs and autoimmune diseases. To optimize immunosuppressive efficacy and minimize adverse reactions, blood CsA and FK506 concentrations need therapeutic drug monitoring to get appropriate concentration window.

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