Influence of the mixing regimen and high sheer mixer filling on the content uniformity of the venlafaxine hydrochloride dry blends

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: FDP-P-17
• By: MAKRADULI, Liljana (Replek Farm Ltd., Research & Development, Skopje, Macedonia)
• Co-author(s): Ristevska, E. (Replek Farm Ltd., Skopje, Macedonia)
  Anevska, M. (Replek Farm Ltd., Skopje, Macedonia)
  Adamova, E. (Replek Farm Ltd., Skopje, Macedonia)
  Sekovanic, A. (Replek Farm Ltd., Skopje, Macedonia)
  Ivceska, L. (Replek Farm Ltd., Skopje, Macedonia)
  Lepcevska, D. (Replek Farm Ltd., Skopje, Macedonia)
  Dimova, D. (Replek Farm Ltd., Skopje, Macedonia)
  Dameska, R. (Replek Farm Ltd., Skopje, Macedonia)
  Pejic, T. (Replek Farm Ltd., Skopje, Macedonia)
  
• Abstract:

  Dry mixing is the most common mixing approach used for manufacture of homogenous dry blends of active substances and excipients. The homogenisation of the active substances is a critical factor that often influences the content uniformity of many pharmaceutical dossage forms, especially tablets and capsules. The objective of this study was to

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