Hydrocortisone dermal bioavailability from alkyl polyglucoside emulsifier-stabilised bases: in vivo skin blanching assay

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: FDP-P-21
• By: PANTELIC, Ivana (University of Belgrade - Faculty of Pharmacy, Department of Pharmaceutical Technology and Cosmetology, Belgrade, Serbia)
• Co-author(s): Lukic, M. (University of Belgrade - Faculty of Pharmacy, Belgrade, Serbia)
  Milic, J. (University of Belgrade - Faculty of Pharmacy, Belgrade, Serbia)
  Vuleta, G. (University of Belgrade - Faculty of Pharmacy, Belgrade, Serbia)
  Savic, S. (University of Belgrade - Faculty of Pharmacy, Belgrade, Serbia)
  
• Abstract:

  Corticosteroids, the most frequently prescribed topical drugs, are known to induce skin blanching through vasoconstriction of cutaneous vessels which is employed for their dermal bioavailability assessment.The aim of this work was to compare hydrocortisone (HC) skin absorption from bases stabilized with a natural-origin alkyl polyglucoside

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