Rapid determination of GSTP1 promoter methylation using differential high resolution melting analysis

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: BIO-P-07
• By: NAGHI TORABI, Mojgan (Isfahan University of Medical Sciences, Dept. of Pharmaceutical Biotechnology, Isfahan, Iran)
• Co-author(s): Mohammadi Asl, J. (Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran)
  Mir Mohammad Sadeghi, M. (Isfahan University of Medical Sciences, Isfahan, Iran)
  Rabbani, M. (Isfahan University of Medical Sciences, Isfahan, Iran)
  Jafarian Dehkordi, A. (Isfahan University of Medical Sciences, Isfahan, Iran)
  
• Abstract:

  I. DNA methylation is one of the key regulators of gene expression. It also has an important role in carcinogenesis through epigenetic silencing of tumor suppressor and DNA repair genes. DNA hyper methylation inpromoter region of glutathione S-transferase pi 1 (GSTP1) gene has been detected in a variety of cancers such as breast cancer. As studies

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