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Synthesis and antimycobacterial activity of novel 5-substituted-4-thiazolidinone-n-amino acid derivatives

  • In: SIG Posters
  • At: Amsterdam (the Netherlands) (2012)
  • Type: Poster
  • Poster code: DDD-P-06
  • By: SLEPIKAS, Liudas (University of Geneva, Geneva, Switzerland)
  • Co-author(s): Kicka, S. (University of Geneva, Geneva, Switzerland)
    Ouertatani-Sakouhi, H. (Centre Medical Universitaire Department of Cell Physiology and Metabolism, Geneva, Switzerland)
    Bisson, W. (University of Geneva, Geneva, Switzerland)
    Tarsevicius, E. (Lithuanian University of Health Sciences, Kaunas, Lithuania)
    Scapozza, L. (University of Geneva, Geneva, Switzerland)
  • Abstract:

    I.Many compounds bearing the 4-thiazolidinone chemical scaffold have been reported to have antimicrobial activity.II.The aims of this work are to develop new 5-substituted 4-thiazolidinone -N-amino acid derivatives with improved activity and selectivity against
    Mycobacterium

    and eventually other pathogens such as
    Klebsiella


    pneumoniae

    ,
    Pseudomonas

    ..

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Last update 28 September 2023

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