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Rational design of new azole compounds and their potent inhibitory effects on fungal growth
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-036-Monday
- By: SARI, Suat (Ankara, Turkey)
- Co-author(s): Suat Sari: Department of Pharmaceutical Chemistry, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
Didem Kart: Department of Pharmaceutical Microbiology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
Arzu Karakurt: Department of Pharmaceutical Chemistry, Inonu University Faculty of Pharmacy, Malatya, Turkey
Selma Saraç: Department of Pharmaceutical Chemistry, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
Sebnem G. Essiz: Bioinformatics and Genetics Department, Kadir Has University Faculty of Engineering and Natural Sciences, Istanbul, Turkey
Sevim Dalkara: Department of Pharmaceutical Chemistry, Hacettepe University Faculty of Pharmacy, Ankara, Turkey - Abstract:
Backgrounds
Invasive candidiasis is a serious health threat for immune-compromised patients. Candida albicans is the most common species, yet non-albicans Candida (naC) infections with high mortality and drug resistance have been reported. Azole antifungals, which target fungal lanosterol 14 α-demethylase (CYP51), are a class of choice in invasive
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Last update 28 September 2023