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Synthetic studies toward a quinolinone alkaloid aspoquinolone A possessing potent antiproliferative activity
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-044-Monday
- By: TSUBUKI, Masayoshi (Hoshi University, Tokyo, Japan)
- Co-author(s): Masayoshi Tsubuki: Hoshi University, Tokyo, Japan
Takumi Hosozawa: Rikkyo University, Tokyo, Japan
Hiromasa Yokoe: Hoshi University, Tokyo, Japan
Hiroaki Tokiwa: Rikkyo University, Tokyo, Japan - Abstract:
Backgrounds
Recently, aspoquinolone A (1), a quinolinone alkaloid, has been isolated from Aspergillus nidulans (HKI 0410) by Hertweck et al. and exhibits high cytotoxicity against L-929 mouse fibroblast cell lines (GI50 10.6 μg ml-1) and good antiproliferative effects on human leukemia cell line K-562 (GI50 17.8 μg ml-1). The structural features of .. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023