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Enhancing effect of aspirin on intestinal absorption of gliadin, wheat allergen, and its mechanism
- At: Glasgow (Scotland) (2018)
- Type: Poster
- Poster code: POS-PAA-016
- By: YOKOOJI, Tomoharu (Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Pharmaceutical Services)
- Co-author(s): Tomoharu Yokooji: Department of Pharmaceutical Services, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan;School of Pharmaceutical Sciences, Hiroshima University, Hiroshima, Japan
Koh Hamura: School of Pharmaceutical Sciences, Hiroshima University, Hiroshima, Japan
Naoki Ninomiya: School of Pharmaceutical Sciences, Hiroshima University, Hiroshima, Japan
Takanori Taogoshi: Department of Pharmaceutical Services, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
Hiroaki Matsuo: Department of Pharmaceutical Services, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan - Abstract:
Background
Food allergens are absorbed from the intestinal lumen and exhibit their allergenicity. Aspirin exacerbates the food-allergic symptoms by increasing absorption of ingested allergens.
Methods
To evaluate the gliadin absorption, plasma concentrations were measured after oral administration by gavage or into a closed intestinal loop in rats.
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Last update 28 September 2023