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In vitro evaluation of the cytotoxic, antibacterial and antioxidant properties of selected chitosan derivatives and melittin
- In: Poster presentation
- At: Buenos Aires (Argentina) (2016)
- Type: Poster
- Poster code: POS-FDP-003
- By: DU PLESSIS, Lissinda (North-West University Potchefstrrom Campus, Pharmaceutics, Potchefstroom, South Africa)
- Co-author(s): Lissinda Du Plessis:Pharmaceutics,North-West University Potchefstrrom Campus,Potchefstroom,South Africa|Garmi Jacobs:|Jaco Wentzel:|Sandy van Vuuren:Pharmacy and Pharmacology,Univerisity of the Witwatersrand,Johannesburg,South Africa|Awie Kotze:
- Abstract:
There is an increasing need for new functional excipients. We synthesized a wide range of more soluble chitosan derivatives to be used as absorption enhancers. Chitosan derivatives, in combination with melittin, a cationic antimicrobial peptide, has proven synergistic absorption effects in vitro.
In vitro evaluation was performed on HepG2 and
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Last update 28 September 2023