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Protein surfactant interaction and temperature dependent adsorption: g-scf formulation
- In: SUBMITTED ORAL on Monday, 14 April 2014, 16:00-17:30
- At: PSWC, Melbourne (Australia) (2014)
- Type: Presentation
- By: BREMMELL, Kristen (University of South Australia, School of Pharmacy and Medical Sciences, Adelaide, Australia)
- Co-author(s): Chang, Patrick (University of South Australia, Adelaide, Australia)
Kempson, Ivan (University of South Australia, Adelaide, Australia)
Barnes, Tim (University of South Australia, Adelaide, Australia)
Prestidge, Clive (University of South Australia, Adelaide, Australia) - Abstract:
Background: Therapeutic proteins require careful formulation to maximize physical stability and retain their native conformation and commonly include the addition of non-ionic surfactants to aid in reducing protein aggregation and adsorption at interfaces.
Methods: Interaction between the non-ionic surfactant polysorbate 20 and the therapeutic.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023