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Development of Hydroxy-Based SphK Inhibitors and Anti-Inflammation in DSS Induced Colitis in Mice
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-051-Monday
- By: XI, Meiyang (Beijing, China)
- Co-author(s): Meiyang Xi: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Xiaojian Wang: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Qiong Xiao: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Hui Wen: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Xiang Zhang: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Huaqing Cui: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
Dali Yin: Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China - Abstract:
Backgrounds
Sphingosine kinase (SphK)-catalyzed production of sphingosine-1-phosphate (S1P) regulates cell growth, survival and proliferation as well as inflammatory status in animals.Aims
to find an anti-inflammatory agent to probably treat inflammatory bowel diseases in human.Methods
SAR DSS induced mouse modelsResults
In recent study we.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023