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Docking studies, synthesis, characterization and evaluation of antitumor activity of some novel thiazine substituted 9-anilinoacridines and their 3d qsar studies
- In: Posters: Drug Design and Discovery
- At: Bangkok (Thailand) (2014)
- Type: Poster
- Poster code: POS-DDD009
- By: RAJAGOPAL, Kalirajan (JSS College of Pharmacy, Department of Pharmaceutical Chemistry, The nilgiris, India)
- Co-author(s): Sundaram, Sankar (JSS College of Pharmacy, The nilgiris, India)
Selvaraj, Jubie (JSS College of Pharmacy, Ootacamund, India) - Abstract:
Background information:
Acridine analogues bearing substituted bulky 9-amino functionalities are shown to inhibit topoisomerase II, relaxation of super coiled DNA are important drugs in treatment of cancer.
Aims
Based on the above background, A series of novel thiazine substituted 9-anilinoacridines were synthesized and evaluated for antitumor.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023