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Effects of glutathione depletion on diclofenac-induced cytotoxicity in mouse hepatocytes
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-025-Tuesday
- By: KAWASE, Atsushi (Kindai University, Department of Pharmacy, Osaka, Japan)
- Co-author(s): Atsushi Kawase: Department of Pharmacy, Kindai University, Osaka, Japan
Ayaka Kaneto: Department of Pharmacy, Kindai University, Osaka, Japan
Mao Ishibashi: Department of Pharmacy, Kindai University, Osaka, Japan
Hiroaki Shimada: Department of Pharmacy, Kindai University, Osaka, Japan
Masahiro Iwaki: Department of Pharmacy, Kindai University, Osaka, Japan - Abstract:
Backgrounds
Idiosyncratic drug-induced liver injury (DILI) with certain drugs is usually rare, but has serious consequences and is the most common reason for drugs to be withdrawn from the pharmaceutical market. It is difficult to predict its occurrence during preclinical and clinical trials, because the mechanisms of idiosyncratic DILI are still.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023