Export this Abstract | Print this Abstract | Add to my preferred Abstracts list | My preferred Abstracts list (0) | Back to Search
The new pH sensitive polycation improves the transfection activity of R8-modified lipid nanoparticles by facilitating siRNA condensation
- In: SIG Posters
- At: Amsterdam (the Netherlands) (2012)
- Type: Poster
- Poster code: FDP-P-28
- By: TORIYABE, Naoyuki (Hokkaido University, Faculty of Pharmaceutical Science, Sapporo, Japan)
- Co-author(s): Hayashio, Y. (Hokkaido University, Sapporo, Japan)
Akita, H. (Hokkaido University, Sapporo, Japan)
Harashima, H. (Hokkaido University, Sapporo, Japan) - Abstract:
..
?. Background
We previously developed octaarginine (R8) and GALA, as a pH-sensitive fusogenic peptide modified a lipid Double-lamellar Multifunctional Envelope-type Nanoparticles Device (R8/GALA-D-MEND) for siRNA delivery. Herein, we report whether a new pH sensitive polycation (pHSP), as a siRNA condensed polycation in response to pH difference, The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
Please login
Last update 28 September 2023